Weight Loss Peptides

Jul 28, 2025

Table of Contents

Meet the Author

Jeff Bio

Jeff Robinson

Why Hellooo there!! 🙂
My name is Jeff Robinson, I am a 38 year old “Biohacker”, Coach, Dad, Husband who is completely obsessed with Health optimization!

How to best utilize these ranked lists:

The purpose of doing ranked list based on goal was to give people a way to QUICKLY narrow down which peptide MAY work best for your individual goals.

There are over 40 peptides currently available and it can be a daunting task to choose which peptides to try first.

This list will help save you time and money by choosing the peptides that will most likely work best for your particular health goals!

Important Considerations:

  • You will see some peptides referenced multiple times for different health goals. Many peptides have PLEIOTROPIC effects meaning they can benefit a wide range of bodily systems and functions.
  • These ranked lists are based on GENERAL CONSENSUS meaning the peptides that most consistently work for the MOST people for a particular issue and or goal.
  • It is important to understand there are always outliers with every peptide.
  • You have some individuals who will be hyper responders, who notice benefits very quickly and get rapid results.
  • You also have individuals on the other side of the spectrum who may be total non responders. There’s a spectrum of results responses with each peptide.
  • There is NEVER a one size fits all approach for any condition and or person.
  • I did my best to get them ranked by which ones we have the most and best feedback on per goal!!
  • Hope it offers some value 🙂

BEST Peptides for Weight Loss:

Tier ONE: (Best of the Best – The most proven effective options for weight loss)

  1. Tirzepatide (Dual Agonist GIP/GLP-1, FDA Approved Diabetes, GAME CHANGER)
  2. Retatrutide (TRIPLE agonist GLP-1 that is even more effective than Tirz for some!!)
  3. Cagrilinitide – CagriSema – CagriTirz. Cagri is NOT a GLP-1 peptide but feedback is extremely positive. Researchers are stacking it w/ Sema or Tirz to break plateaus and/or use Cagri as a standalone weight loss agent.
  4. Survodutide – Less feedback overall, but it’s a DUAL AGONIST GLP-1 that I predict will continue to produce excellent results. The feedback I do have is extremely positive.
  5. Semaglutide – It may not be a crowd favorite anymore, but still highly effective for a good portion of people.

Tier TWO:

  1. CJC 1295/Ipamorelin (Growth Hormone Releasing Hormone / Growth Hormone Releasing Peptide)
  2. Tesamorelin/Ipamorelin (Growth Hormone Releasing Hormone / Growth Hormone Releasing Peptide)
  3. Mots C / SS31 (Aids in Fat Metabolism, Studied for Metabolic Syndrome, Mitochondrial Derived Peptide)
  4. AOD 9604 (Feedback has not impressed me, but it gets promoted frequently for weight loss. At best, this to me is a FINAL piece to consider stacking, in my opinion.)

Tier Three:

  1. 5 AMINO 1MQ (oral, not a peptide) (Studied for Obesity, May Boost Muscle Repair and Reduce Muscle Wasting)
  2. Tesofensine

Community Voted Favorite Peptide Suppliers for Above Peptides

(Peptides purchased direct ONLINE are sold “For Research Purposes ONLY”)


ATOMIK Peptides 🇺🇸
(T Research) – 3rd Party Batch Tested
Use Discount code Biohacked15 (15% off)
https://atomiklabz.com


Solution Peptides 🇺🇸
Community Voted #1 Fav Supplier in 2024 Polls
Group Discount Code Biohacked15 (15% off)
https://solutionpeptides.com


Limitless Life Nootropics 🇺🇸
Community Voted #2 Fav Supplier in 2024 Polls
Group Discount Code Biohacked20 (20% off)
https://www.limitlesslifenootropics.com


DN Lab Research 🇬🇧🇪🇺🇦🇪
Fully operational for UK/EU and UAE Members!!
Discount Code Biohacked15 (15% off)
https://dnlabresearch.com

ATOMIK LABZ & Solution Peptides Ordering LEGEND:

  • On both sites GLPs are under these different names for cautionary reasons
  • ATOMIK is Solution’s “sister” company separated to offer a very particular peptide


ATOMIK LABZ 🇺🇸
Only group vetted source for Tirz right now*
Group Discount Code: Biohacked15 (15% off)
https://atomiklabz.com


Solution Peptides 🇺🇸
2024 1st Place in Voting for Favorite Peptide Supplier!!
(Reta, Sema, NAD+, Peptides, Vitamins)
Full 3rd party testing reports and great feedback from community on this supplier.
Group Discount Code: Biohacked15 (15% off)
https://solutionpeptides.net

QUICK Notes on Best Weight Loss Peptides:

The GLP1 Peptides and Cagrilinitide truly are in a class of their own. In my 15 years of coaching I’ve never seen anything come even remotely close for weight loss. There’s truly never even been another compound that I found highly effective and SAFE. The GLP-1 peptides have changed the weight loss industry forever and when these peptides are used properly they can be absolutely life changing. But these are powerful peptides that require a comprehensive understanding how to utilize.

To get BEST results and prevent muscle wasting, individuals need to have ALL foundational aspects to their health addressed — including proper diet, exercise, and good lifestyle practices.

Weight TRAINING is CRUCIAL – Yes ladies that means YOU 🙂 No you will not get “bulky” unless you’re taking mega doses of Testosterone, which I know you’re not. Lifting weights is how you get that TONED look and don’t end up skinny fat from muscle wasting… Got to lift!!

Lift Heavy, make SURE you get enough protein, make sure to eat enough calories — extreme caloric deficit WILL cause muscle loss which SLOWS your metabolism! Slow metabolism badddd 🙂

Common sense yes, I know — but in order to get SUSTAINABLE weight loss, individuals HAVE to optimize all facets of health and lifestyle to achieve LASTING weight loss. These are powerful tools, but the WORK cannot be skipped if people want the best results 🙂

It is also extremely important to have comprehensive hormone evaluation if weight loss has been a chronic struggle. Optimized hormones are absolutely crucial to getting best results on any weight loss program.

What about TESOFENSINE?
As of NOW 11/20/24 I am still hesitant to recommend this compound. I advise very careful research and consideration.

YES, some people absolutely LOVE it — but for some, it messes with sleep and leaves them extremely overstimulated.

This is a newer compound (not peptide) that I see being sold and promoted for weight loss frequently now. I have positive feedback, and I have some very concerning feedback. Tesofensine has an extremely long half life and is a triple reuptake inhibitor for neurotransmitters. This mechanism of action I can see being extremely problematic for some people. I want to see more/better studies on this compound.

Please be fully aware of the PROs and Potential Cons with this very powerful DRUG.

What about Cjc1295/Ipamorelin, Tesamorelin, Mots C?

Let me start by saying I absolutely love these peptides.

Optimizing growth hormone NATURALLY with these peptides is extremely beneficial and the community feedback is super consistent that many notice real benefits from these peptides.

BUT!!

In regards to consistent and significant WEIGHT LOSS, these peptides get a bit overhyped…

They absolutely can aid and support weight loss when all the other variables involved with weight loss are addressed. But as a standalone treatment to lose weight, I would not expect significant and/or rapid weight loss.

Can they result in some weight loss as a standalone? YES — it’s definitely possible and reported, but it’s just not the level of weight loss we see with the TOP options.

That being said, I absolutely believe for any weight loss program, using these tools would be a fantastic piece to that puzzle. Stacking these peptides with Tirzepatide or Semaglutide, in my opinion/experience, is a fantastic combination that works well together.

But I don’t want people being misled to believe using Cjc1295/Ipamorelin and/or Tesamorelin will just magically shred fat. That’s unfortunately not the case!!

These are amazing peptides for anti-aging, overall health, sleep, and recovery.

GH peptides are top 5 all around in my opinion!!!!

Suppliers I Personally Vet

Full List of Suppliers I personally VET: 

I know the owners, I know their customer service teams and I WILL STEP in to help with ANY issues with your orders!!

If you love the content and want to support using my affiliate links it’s greatly appreciated and helps me afford the time to make high quality FREE content for the community which I love doing 🙂

But no pressure!! Even if you just support by just giving quality feedback in the group and good vibes thats appreciated too!! 🙂

 

**ATOMIK Peptides 🇺🇸
(Tirz Research) – 3rd Party Batch Tested
-Full 3rd party testing reports
Use Discount code Biohacked15 (15% off)
https://atomiklabz.com

ScantiFix 🇺🇸
Newest company I personally vet, DIY Peptide Skincare, Hair-Skin Tech products & Oral Peptide Formulations!
Use Discount code Biohacked15 (15% off)
https://www.scantifix.com/

Solution Peptides 🇺🇸
(2024 1st Place in Voting for Favorite Peptide Supplier!!)
(Reta, Sema, NAD+, Peptides, Vitamins)
-Full 3rd party testing reports and great feedback from community on this supplier.** **
Group Discount Code: Biohacked15 (15% off)
https://solutionpeptides.net

Limitless Life Nootropics 🇺🇸
(2024 2nd Place in Voting for Favorite Peptide Supplier!!)
-Full 3rd party testing reports
Group Discount Code: Biohacked20 (20% OFF)
https://www.limitlesslifenootropics.com

BioSynergen Peptides: 🇨🇦
Tirz Research Stocked
-Full 3rd party testing reports
Group Discount code: Biohacked10 (10% off)
https://biosynergen.com

CosmicNootropic.com
(Cerebrolysin, Cortexin, Peptide Bioregulators)
Group Discount Code: projectbiohacked10 (10% off)
https://cosmicnootropic.com

LVLUPhealth.com
*For the BEST Oral Peptide Formulations – GI Healing – BPC157
*Group Discount Code: Biohacked10 (10% off)
https://lvluphealth.com/en-us

DN Lab Research is fully operational for our **UK/EU and UAE Members!! **
-Full 3rd party testing reports
Discount Code: Biohacked15 (15% off)
https://dnlabresearch.com

Promethean Bioregulators
US Based Peptide Bioregulator supplier:
Group Discount Code: Biohacked10 (10% off)
https://www.probr.com

About Promethean:

  • They have FULL line of CYTOMAX Bioregulators. These are the full strength natural bioregulators that you see being sold at Cosmic, Qi, Profound Health ETC. They are batch tested for purity and have all the quality reports for each product.
  • They STOCK and SHIP from the US!! AKA Fast Shipping
  • Boxes each contain 20 caps which covers a STANDARD protocol of 2 caps per day for 10 days. Approaches vary depending on individuals health goal/situation/severity.

ATOMIK LABZ & Solution Peptides Ordering LEGEND
On both sites GLPs are under these different names for cautionary reasons

ATOMIK LABZ 🇺🇸
Only group vetted source for Tirz right now*
Group Discount Code: Biohacked15 (15% off)
https://atomiklabz.com

Solution Peptides 🇺🇸
(2024 1st Place in Voting for Favorite Peptide Supplier!!)
(Reta, Sema, NAD+, Peptides, Vitamins)
Full 3rd party testing reports and great feedback from community on this supplier.** **
Group Discount Code: **Biohacked15 **15% off
https://solutionpeptides.net

ATOMIK LABZ & Solution Peptides Ordering Legend

About the Author

Jeff-Bio-225x300

Jeff Robinson B.S. Exercise Physiology Human Performance – Project Biohacked LLC

I graduated from Southern CT University in 2011 with a Bachelors Degree in Exercise Physiology Human Performance.

I’ve been health coaching/consulting privately now for 15+ years and have worked with individuals of all ages and health concerns/goals.

Professional Work Experience:

  • Griffen Hospital Cardiac Rehab
  • Yale Strength and Conditioning
  • IAP Sports Training
  • Revelry Wellness HRT Telehealth Clinic (Now Transcend Wellness)
  • My Summit Health Telehealth Clinic (HRT/TRT, Peptides)

One of my favorite tools to educate clients on is of course PEPTIDE Therapy!!

It’s a tool I’ve seen aid chronic and or acute health struggles when EVERYTHING ELSE had failed.

Peptides really restored my faith in modern medicine, introduced me to the amazing world of regenerative – cellular medicine that is at the cutting edge of health optimization and chronic degenerative conditions.

And these tools have been used for DECADES!! 

There are currently over 100 peptide drugs with FDA approval. 

They are just rarely discussed and Im trying to change that!!  🙂 

I created the health brand Project BioHacked 5 years ago specifically to share about peptide therapy and how it was life changing for my own health struggles. (ADD/ADHD, TBI, PTSD, Anxiety, Depression, Addiction, GI Inflammation)

My “brand” Project BioHacked mission is ALL ABOUT finding the best tools and health/wellness.

The stuff that’s buried far away from mainstream medicine, the stuff that’s proven safe and effective yet is never used by those in the Allopathic Medical system!!

It’s about sharing the REAL GAME CHANGERS for health!

Why did I create Project BioHacked?

It is important to me that people understand my WHY. I want people to fully understand what I am trying to do with the Project BioHacked brand.

This is relevant to peptides since they are one of the tools that forever changed my life for the better and restored my hope I could fully recover my health!

My reason WHY has everything to do with my own at times extremely difficult health journey.

 This life has not always been an easy ride for myself, I have experienced levels of suffering with my own health physically and mentally that I wouldn’t wish upon my worst enemy.

I have been left broken and feeling hopeless from those struggles at the worst points in my life. I have been told by the conventional medical system there’s nothing I can do. That pharmaceutical drugs to suppress symptoms are the only way to manage my struggles.

I have hit that wall in my health over and over again where I felt like I was out of options and destined to suffer through this life. 

 I also know I am not the only one who has gone through and or still has these chronic struggles. I know countless others suffer in silence, bearing a burden that no one even knows about. Too many suffer in silence especially with mental health and or addiction struggles. This includes myself. 

 I have lost loved ones to physical illness and mental health struggles. I think we all know someone who didn’t make it past their physical/mental health struggle. We all have lost people we love. I have seen far too many suffer horribly from these chronic health struggles when the tools to help are available and accessible NOW. 

I have been to the bottom with my health…..but I have also been to the top!

I have experienced the joy of not just recovering physical and mental health but getting to experience all new highs with both. Having the luxury to shift my focus from chronic health to anti-aging and chasing peak physical/mental performance!! 

I have been able to recover and go on to experience days, months and years feeling good again. Days where I have felt happy, at peace and content with life. Days I have been able to be fully present with loved ones and just enjoy the simple things in life.

This is something I wish everyone would get to experience as much as possible in their lives.

I am lucky to have fully recovered from the worst of my health struggles, I am lucky to still be here today, to see my kids grow and be there for my family.

Far too many lose that battle because they lose HOPE. They lose hope because they feel like theres nothing that can help. They believe theres no end to their suffering.

Thankfully I learned this is not TRUE!! There are amazing tools that can get not just. RELIEF but actual healing! Far too many of these amazing tools people simply do not know exist! 

Luckily I found some of these amazing tools that kept that hope alive. Somehow I found a way to survive my health crisis and I made the decision then that I would leave no stone left unturned in this life to not just recover my health but to find the tools to ensure I NEVER experienced that level of suffering again.

I committed myself to try to LEARN EVERYTHING in regards to healing the mind, body and spirit. I would study every facet of medicine, I would try everything that I could afford and access.

My promise to myself was if I somehow did recover my health I would reach back to try and help others.

I would share my story, I would share what helped me and I would make it my mission to try and help others struggling. I would leave a roadmap for those suffering. A roadmap and guide that could possibly help restore hope of better days.

I decided to try and create the resource that I wish existed when my health fell apart.

A resource that could quickly get someone to the tools that can make all the difference in their health struggles and goals. A resource that helped restore HOPE that just maybe better days were still possible. 

A resource that shares the tools buried far beyond the conventional medical and health system. The “tools” that can change lives but many don’t know even exist.

It took me over 15 years of relentless research trial and error to find all of the tools to aid in my recovery.

Few have that kind of time, resources and energy to take on.

My goal is to help accelerate that process for people. Get people pointed to the life changing tools much earlier in their journey. Hopefully prevent some from experiencing the horrible lows I did in my own health.

At the end of my days I hope to have created a massive DIY health resource that can change lives for the better.

Help people get to experience their true potential, become the best versions of themselves. Help pass along tools that can aid people and the people they love/care about most.

The mission that will never end is to hunt down and share all the best tools in health and wellness. To refine and update these resources every year as better tools and understanding emerges for all ranges of chronic health struggles/recovery.

The focus will go beyond just chronic health struggles, it will deep dive into physical performance and mental performance. Anti aging and the best sustainable practices to feel our best for the longest period of time possible in this life.

What I LOVE is bringing light to not just the best tools but the best practitioners, the best coaches and clinics. The people who understand how to pull all the best tools together to change lives for the better. Bring together and share what I learn from the best minds in health and wellness.

The goal is to create a massive network that can continue to pass these tools to others long after I’m gone.

That is my mission, that is the reason I do what I do 🙂 

I love networking with other health professionals, coaches and biohackers so feel free to reach out if interested in doing a podcast or partnering on a project 🙂

Jeff Robinson
Project Biohacked LLC