Tirzepatide:

Author: Jeff Robinson B.S. Exercise Physiology Human Performance – Project Biohacked LLC

The following is for Informational Purpose ONLY – I AM NOT A MEDICAL PROFESSIONAL

Always consult your physician before making any changes to your medical treatment plan

Does the real-world feedback live up to the HYPE? (Purported Benefits) 

• 100% Tirzepatide lives up to the hype!!
• Weight Loss – easily one of the if not THEE most effective weightless compound of all time. No prior compound has been highly effective and actually HEALTHY for weight loss with real lasting positive changes. (Improves insulin resistance a primary factor in weight loss struggles) 
• Inflammation management – realworld reports go FAR beyond just weight loss. People are noticing significant improvements in a variety of chronic inflammatory conditions. I will be investigating this much further in 2024 – 2025.
• Anti Aging – there is a very strong argument for GLP1 peptides as very powerful anti aging tools. One of the biggest contributors to the worst degenerative health conditions is Insulin Resistance. Insulin resistance increases risk for cancer, heart disease and Alzheimers – Dementia. Theres a community of leading experts that believe Tirzepatide and other GLP1 peptides used at lower doses is an excellent anti aging – disease prevention approach.

For those buying in the US & Canada:

Every company I recommend I personally VET. I know the owners, I know their customers service teams.

I will step in to help if theres any issues at all so feel to tag me in Facebook group if you have any issues!

(Peptides purchased direct online are sold FOR RESEARCH PURPOSES ONLY, they do not come with instructions, the suppliers WILL NOT advise you how to research these compounds. Please do not purchase if you are unfamiliar with how to research these compounds) 

Atomik Labz 

This is the ONLY vendor I currently vet for Tirz 

https://atomiklabz.com

Group Discount code: Biohacked15

THE FINE DETAILS: 

• All products are 3rd Party batch tested, reports can be found right on website
• Theres no modifications to the Tirz, it’s the exact same Tirzep that was found online from research peptide suppliers for last 2 years.
• It comes in lyophilized form w/ mannitol as the buffer/stabilizer which is what the majority of the industry uses except for peptide sciences and limitless.

FAQs:

Do you sell peptides? (Project Biohacked LLC – Jeff Robinson) 

• No, Project Biohacked LLC – Jeff Robinson has NO stake in any peptide company and does NOT sell peptides in any form.
• In regards to Peptides Project Biohacked LLC only functions in area of EDUCATION 🙂
• I have affiliates, partnerships and collaborations with various companies, coaches, doctors, clinics but I DO NOT sell any products in any form and have NO stake (partial ownership)  in any companies.
• My FULL Business Transparency Statement including affiliated companies, coaches, doctors, clinics can be viewed HERE.

Will online vendors tell me how to dose – use these products?

• Unfortunately no, peptides – compounds purchased direct online from research chemical companies will NOT guide individual on usage.
• (HUGE LIABILITY – companies have been shutdown for giving dosing – usage suggestions)
• If you message vendors and suggest HUMAN USAGE they will not answer and may even blacklist – ban individuals.
• SELF EDUCATION is key part of researching online peptides.

Do peptides purchased online come reconstituted? (In liquid form ready for research usage) 

• Unfortunately No, peptides purchased direct online come in powder form (lyophilized)
• The peptides need to be combined with BAC (sterile solution) at the correct ratio based on target dosage.
• Supplies DO NOT come with orders, many website carrying BAC water but not syringes.
• If mixed incorrectly research dosages can be SEVERELY underused and or OVERDOSED. Which will result in significant increased risk of severe side effects for research.

DOSING:

(Educational Purpose ONLY – Project Biohacked LLC – Always consult your physician before making any changes to your medical treatment plan)

The initial dosage of tirzepatide for treatment initiation is 2.5 mg administered SQ once weekly, with the primary goal of initiation rather than glycemic control. After 4 weeks, increase to 5 mg SQ once weekly. For additional glycemic control, escalate the dosage by 2.5 mg after at least 4 weeks on the current dose. The maximum tirzepatide dosage is 15 mg SQ once weekly. If a tirzepatide dose is missed, it should be administered within 4 days (96 hours) if feasible; otherwise, skip the missed dose and return to the regular once-weekly schedule.

https://www.ncbi.nlm.nih.gov/books/NBK585056/#:~:text=The%20initial%20dosage%20of%20tirzepatide,weeks%20on%20the%20current%20dose.

My Personal Microdosing Approach:

(Educational Purpose ONLY – Project Biohacked LLC – Always consult your physician before making any changes to your medical treatment plan)

• The following approach is based on my personal experience trialing 40+ peptides over the last 7 years, direct feedback coaching 250+ people 1 on 1 on peptide therapy and countless reports from my private Facebook community and membership community. 
• My professional background is bachelors degree in exercise physiology human performance. 15+ years coaching consulting with the last 7 years entirely focused on peptide therapy and cellular medicine. I also worked for telehealth clinic that prescribes HRT/TRT along with peptides for 3 years before turning my focus entirely to building Project Biohacked into a Consumer Reports resource for health and wellness.

The Quick & Dirty Examples of Microdosing for Tirzepatide:

Microdosing Examples using Tirzepatide suggested starting dosage of 2.5mg: (Per Clinical Trials)

I like this approach to TEST Dose and gauge tolerance and or as a longer term approach which has been supported that a portion of people simply do not need higher doses to see benefits.

FIND WHAT WORKS FOR YOU 🙂

• 1/2 Microdose approach would be cutting starting dosage to 1.25mg (1,250mcg) which is widely supported with realworld feedback in my community as well as by some of the industry leading experts on peptide therapy.  
• 1/4 Microdose approach would be starting at around 625mcg (.625mg), which to me would be a very conservative low dose that the vast majority of people could research Tirzepatide at and experience little to NO side effects.
• 1/10 Microdose approach would be 250mcg (.25mg), this approach would be worth considering for those of us who are EXTREMELY sensitive and or highly concerned about side effects. At 1/10th dosing I can typically tolerate just about any peptide with little to no side effects and I tend to be a HYPER RESPONDER to exogenous supplements – medications etc. Ive also found this 1/10th rule to also work for clients and community members.
• The most SIMPLE rule of thumb here is the more sensitive you are the lower you go!
• You literally CANT “go to low” on the dosing. Why rush dosing? Being patient means yes you may lose a day or two or at worst a week to test your tolerance and ensure you don’t have side effects. Majority of peptides taking at minimum 2-4+ weeks to have effects so again I see no reason to rush unless it is truly a SEVERE situation.
• Can I go even lower than 1/10th? – Yup!! Again just general guidelines based on my experience
• Can I just just slightly lower then typical dose? – Yup why not!! Find what WORKS for you. The right approach will absolutely vary person to person.
• Some people need higher dosing more frequently, some need much lower dosing and less frequently. All comes down to tolerance and response.
• Find that range where you experience max benefit with minimal to no side effects.

Now for those who want to go DEEP into all the WHYs and Nuances behind microdosing:

FAQs w/ Microdosing

• Microdosing GLP1s including split dosing is a strategy being used by some of the industries best peptide practitioners.
• This approach is supported by the online community with REALWORLD feedback as well as on the medical professional side. But MAINSTREAM practitioners always stick to basic cookie cutter protocols. When working with a medical professional a good sign of a well educated expert is they will utilize microdosing and split dosing with GLPs!! These approach’s are HIGHLY effective at lowering side effects and improving outcomes for patients.

I AM NOT A medical professional the following is for informational purposes only. You will see I say this probably 15-20x per blog…. 🙂 

Do I have to “microdose”!? 

• Absolutely NOT! Theres a number of reasons I do like this more cautious approach which I will cover below but that being said theres a good percentage of individuals who can start right at “therapeutic” dosage ranges and have no issues.
• If you are perfectly healthy, rarely have any issues – reactions – sensitivities to supplements/medications then most likely you can start right at therapeutic dosage ranges with zero issues.
• For everyone else including those who just prefer to be cautious I did my best to lay out below the types of people who may do best with various microdosing research approaches.

What is “microdosing” with peptides? 

• To put very simply it just refers to the approach of dosing BELOW the typical starting and or typical “therapeutic” dosage range
• Ex. Tirzepatides typical starting dose is 2.5mg per clinical trials. A “microdose” would be going lower then 2.5mg to start and or longer term lower dosing.
• There are NO established parameters for micro-dosing it is just a general term to describe a lower dosing approach.

Why Microdose? 

• Based on my personal experience, coaching – consulting and community feedback microdosing is a fantastic way to mitigate potential side effects.
• Microdosing to START a new peptide can help mitigate risk of side effects, mitigate the severity of side effects if they do occur as well as theres the potential individuals respond and notice benefits at lower doses!! Which means they save money!! 🙂
• Also microdosing is being used as a longer term strategy by some simply because they find the lower doses WORK for them!! They start “low” find they are losing weight with minimal side effects so they decide to stay lower until titrating up is deemed necessary.
• The last category I see for microdosing is for longer term usage with anti aging – inflammation management as primary goal.

Who would POTENTIALLY benefit from a microdosing approach? 

• This is based on my personal experience, community and client feedback 
• Individuals who want to trial a longer term usage for general inflammation – anti aging benefits.
• Individuals who simply want to mitigate the risk of side effects when they are researching a new peptide.
• Individuals who tend to be “chemical” sensitive (autoimmune disorders, Lyme, EBV, Mold – CIRs, Chronic infections)
• Individuals who simply find they respond very strongly to exogenous supplements, medications et
• I would consider myself a HYPER RESPONDER, I have always been very caffeine sensitive, prone to immune sensitivities, supplements etc. So microdosing is a PERSONAL approach I always use to start ANY new supplement – peptide so I can gauge my tolerance before titrating up the dose slowly.

How long do I microdose for?

• This is entirely up to the individual and situation – response dependent. This would be great question for my private membership community where myself and community members can give our opinion based on current situation. (Signup information below if ever interested) 
• In general though if TEST Dose goes smooth with zero issues then next scheduled dose I would consider increasing the research subjects dosage. How much to increase is another very difficult to give general rule on so another one private membership would be ideal for!

Microdosing Ranges:

(Again these are general guidelines based on my personal experience) 

• 1/2 dose – great approach for those who are generally in good health w/ low tendency towards supplement – medication sensitivities. This would be my preferred TEST DOSE for the vast majority of people to simply gauge their personal tolerance and response to a NEW peptide. For individuals who simply want to mitigate risk of side effects when trialing a new peptide 1/2 approach is typically very effective for MOST people. Individual can quickly titrate to therapeutic – target dosage once gauging response and making sure no unwanted side effects occur.
• 1/4 dose – this approach I would consider good for those who are more sensitive to supplements and medications. Who possibly are dealing with a mild – moderate severity chronic health condition. Again most frequently I am using this kind of approach to TEST DOSE and gauge tolerance for a new peptide, supplement, treatment etc. This would be ideal for those who are concerned about side effects and want to er on the side of caution.
• 1/10 dose – this approach I reserve for hyper responders like myself!! This is best for individuals who are dealing with acute and or chronic immune dysregulation. Lyme, EBV, Mold – CIRs, Autoimmune conditions and or just simply very sensitive to supplements. This would be an approach to TEST response to new peptides and titrating would be best done extremely slow while watching for symptom flares. IF a flare occurs which can be any usual side effect that MAY be related to the peptide usage my personal approach is to stop immediately and wait til the “flare” subsides. Then lower dose and reintroduce. If another flare occurs this can be repeated until tolerance is gauged and or it may be best to just pivot to a different peptide! I have found certain peptides just do NOT agree with myself and or others no matter how low we go 🙁
• Can I go even lower than 1/10th? – Yup!! Again just general guidelines based on my experience
• Can I just just slightly lower then typical dose? – Yup why not!! Find what WORKS for you. The right approach will absolutely vary person to person.
• Some people need higher dosing more frequently, some need much lower dosing and less frequently. All comes down to tolerance and response.
• Find that range where you experience max benefit with minimal to no side effects.

Who else may consider “Microdosing”? 

• To quickly review
• I like Microdosing as an approach to TEST the tolerance for a new peptide, supplement, treatment which in turn mitigates the risk and severity of side effects IF they occur.
• I like Microdosing approach for those who are immune compromised and or have severe immune dysfunction and or just sensitive in general.
• The final case situation I like microdosing is for longer duration usage for ANTI AGING – Inflammation management!! This approach is being discussed by industry leading practitioners on peptide therapy as a powerful way to lower inflammation and fight aging.
• Chronic inflammation is one of the KEY contributors accelerated aging and DISEASE. Peptides manage inflammation by actual HEALING better then anything ive ever seen so not surprising its being viewed as a way to slow aging but also just simply increase quality of LIFE.
• I.E less pain, faster recovery, bette energy, better mood, cognitive function etc etc 🙂

Microdosing Examples using Tirzepatide suggested starting dosage of 2.5mg: (Per Clinical Trials)

• 1/2 Microdose approach would be cutting starting dosage to 1.25mg (1,250mcg) which is widely supported with realworld feedback in the community.
• 1/4 Microdose approach would be starting at around 625mcg (.625mg), which to me would be a very conservative low dose that the vast majority of people could research Tirzepatide at and experience little to NO side effects.
• 1/10 Microdose approach would be 250mcg (.25mg), this approach would be worth considering for those of us who are EXTREMELY sensitive and or highly concerned about side effects. At 1/10th dosing I can typically tolerate just about any peptide with little to no side effects.
• The most SIMPLE rule of thumb here is the more sensitive you are the lower you go! You literally CANT “go to low” on the dosing. Why rush dosing? Being patient means yes you may lose a day or two or at worst a week to test your tolerance and ensure you don’t have side effects. Majority of peptides taking at minimum 2-4+ weeks to have effects so again I see no reason to rush unless it is truly a SEVERE situation.

My experience and or community feedback:

Contraindications:

– Always speak to your medical professional and or independently research each compound to consider potential pros – cons and interactions with any medications.

If you need help learning how to safely RESEARCH Peptide Therapies!!

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