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Cerebrolysin

Aug 5, 2025

Table of Contents

What is Cerebrolysin

Who May Benefit

Does Cerebrolysin Meet The Hype

How Does Cerebrolysin Work?

Review Of Studies of Cerebrolysin

Does Cerebrolysin Have FDA Approval?

Vetted Suppliers for Cerebrolysin

Dosing

Other Resources

Sample Protocol

PRIONS Risk

Suppliers I Personally Vet

About the Author

Mission Statement

Meet the Author

Jeff Bio

Jeff Robinson

Why Hellooo there!! 🙂
My name is Jeff Robinson, I am a 38 year old “Biohacker”, Coach, Dad, Husband who is completely obsessed with Health optimization!

The following is for INFORMATIONAL Purposes only, this is NOT MEDICAL advice, I AM NOT a medical professional, please consult with your physician before making any changes to your medical treatment plan.

Peptides purchased DIRECT ONLINE are sold for research purposes only, the following information is for REGISTERED researchers.

⚠️ QUICK Note: I would not advise trialing Cerebrolysin as a “novice” biohacker. This is a Biologic drug approved in over 40 countries, it comes in liquid form in a glass ampule. It requires careful research to administer properly and a comprehensive understanding of potential side effects. 

PLEASE DO NOT research this without fully understanding pros and potential cons. 

What is Cerebrolysin:

Cerebrolysin (developmental code name FPF-1070) is a neuropeptide mixture of enzymatically-treated peptides derived from porcine whose constituents can include brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF).[3][4] Although it is under preliminary study for its potential to treat various brain diseases, it is used as a therapy in dozens of countries in Eurasia.

Cerebrolysin remains a widely used neuropeptide-based drug with over five decades of clinical application. While its efficacy is still debated in some scientific circles, its long-standing clinical history, safety profile, and neuroprotective properties have cemented its place in many neurological treatment protocols worldwide.

Who May Benefit from Cerebrolysin:

Neurodevelopmental Disorders

Includes: Attention Deficit Disorder (ADD) & Attention Deficit Hyperactivity Disorder (ADHD)

Benefits:
  • Enhances dopaminergic and noradrenergic function, which are often dysregulated in ADHD.
  • Improves focus, attention span, and impulse control.
  • May promote better learning ability and memory consolidation.
  • Supports brain plasticity, which is beneficial in neurodevelopmental disorders.

Cognitive Enhancement (Nootropic Use)

Commonly used by students, professionals, and those experiencing cognitive decline.

Benefits:
  • Enhances memory formation and recall.
  • Increases mental clarity and alertness.
  • May improve processing speed and executive function.
  • Supports synaptic plasticity, which is essential for learning and intelligence.

Memory Impairment & Dementia

Includes: Alzheimer’s Disease, Vascular Dementia, and Mild Cognitive Impairment (MCI)

Benefits:
  • May slow neurodegeneration and disease progression.
  • Enhances cholinergic function, which is vital for memory and learning.
  • Reduces oxidative stress and inflammation, two major factors in dementia.
  • Supports nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) for neuroprotection.

Brain Fog & Mental Fatigue

Benefits:
  • Helps reduce cognitive sluggishness and mental fatigue.
  • Supports mitochondrial energy production, combating mental exhaustion.
  • Reduces oxidative stress and neuroinflammation, which contribute to brain fog.
  • Useful for individuals experiencing post-viral fatigue, stress-related cognitive dysfunction, or metabolic brain disorders.

Neuroinflammation & Neuroprotection

Includes: Chronic Neuroinflammation, Autoimmune Brain Disorders (e.g., MS), Post-COVID Brain Fog

Benefits:
  • Reduces neuroinflammation by modulating microglial activity.
  • Helps repair neuronal damage caused by chronic inflammation.
  • Protects against excitotoxicity, which is implicated in neurodegenerative diseases.
  • Potential benefits for multiple sclerosis (MS), neuro-Lyme disease, and post-COVID neurological symptoms.

Stroke Recovery & Traumatic Brain Injury (TBI)

Used in rehabilitation settings for patients recovering from ischemic stroke or traumatic brain injuries.

Benefits:
  • Supports brain repair and neuroplasticity after stroke or head trauma.
  • Improves motor function and cognitive recovery post-injury.
  • Reduces glial scarring, which can interfere with brain healing.

Parkinson’s Disease & Motor Disorders

Potential as a complementary therapy for Parkinson’s and other movement disorders.

Benefits:
  • May slow dopaminergic neuron degeneration.
  • Enhances motor function, balance, and coordination.
  • Improves cognitive symptoms associated with Parkinson’s disease.

Autism Spectrum Disorder (ASD) & Developmental Delays

Benefits:
  • May improve social skills and verbal communication.
  • Enhances cognitive function and learning ability.
  • Supports brain connectivity and neurodevelopment.
  • Some studies suggest benefits in children with ASD, though more research is needed.

Mood Disorders (Depression, Anxiety, PTSD, Burnout)

Used in treatment-resistant depression and anxiety disorders as an adjunct therapy.

Benefits:
  • Enhances neurogenesis and synaptic plasticity, which are impaired in depression.
  • May reduce anxiety by balancing neurotransmitter activity.
  • Supports stress resilience by improving brain metabolism.
  • Potentially aids in PTSD recovery by modulating brain repair mechanisms.

Peripheral Neuropathy & Nerve Regeneration

Experimental use in peripheral nerve repair.

Benefits:
  • May support nerve regeneration in peripheral neuropathy.
  • Helps with diabetic neuropathy and nerve damage from toxins.

Conclusion: Who May Benefit?

  • Individuals with ADD/ADHD seeking better focus and cognitive function.
  • Those experiencing brain fog, fatigue, and mental burnout.
  • People looking for memory enhancement and nootropic effects.
  • Patients with Alzheimer’s, dementia, or mild cognitive impairment.
  • Individuals with stroke, TBI, or neuroinflammation seeking recovery.
  • Those with Parkinson’s, MS, or other neurodegenerative diseases.
  • Patients suffering from chronic stress, anxiety, PTSD, or depression.

Caution: Cerebrolysin is a prescription medication in many countries and should be used under medical supervision. Side effects can include headaches, agitation, dizziness, or allergic reactions.

Neuroinflammation in COVID-19:

Research indicates that SARS-CoV-2 infection can lead to neuroinflammation, affecting brain regions essential for functions such as memory, learning, and emotional responses. Studies have observed microglial activation and the expression of inflammatory cytokines like interleukin (IL)-1β and IL-6 in the brains of individuals with COVID-19. These inflammatory responses can disrupt brain vasculature integrity, neurotransmission, and neurogenesis, potentially contributing to cognitive deficits observed in COVID-19 patients. pmc.ncbi.nlm.nih.gov

Potential Benefits of Cerebrolysin for LONG COVID:

Cerebrolysin has been investigated for its ability to modulate neuroinflammation and promote neuronal regeneration. In the context of COVID-19, its potential benefits include:

  • Neuroprotective Effects: Cerebrolysin may help reduce neuroinflammation by modulating the activity of microglia, the brain’s resident immune cells. This modulation can potentially alleviate the inflammatory responses induced by SARS-CoV-2 infection.
  • Enhancement of Neuronal Regeneration: By promoting neuronal regeneration, Cerebrolysin may aid in repairing brain regions affected by COVID-19-related neuroinflammation, thereby improving cognitive functions.
Considerations:

While preliminary studies suggest that Cerebrolysin may offer neuroprotective benefits in the context of COVID-19, further research, including clinical trials, is necessary to confirm its efficacy and safety. Patients should consult with healthcare providers before considering Cerebrolysin as a treatment option for COVID-19-related neuroinflammation.

QUICK NOTE on Cerebrolysin and Cancer: 

Antitumor Potential:

A study conducted on mice with Lewis lung carcinoma evaluated Cerebrolysin’s impact on tumor growth and metastasis. The findings revealed that Cerebrolysin administration led to a significant suppression of tumor growth rates by 10-15% and a dose-dependent reduction in the number of large metastases by 30-50%. pubmed.ncbi.nlm.nih.gov

Protection Against Chemotherapy-Induced Cognitive Impairment:

Chemotherapy-induced cognitive impairment, often referred to as “chemobrain,” affects a substantial number of cancer patients undergoing treatment. Research involving mice treated with the chemotherapy agent carmustine demonstrated that Cerebrolysin administration improved cognitive functions, reduced oxidative stress markers, decreased inflammatory cytokine levels, and restored neurotransmitter concentrations. These results suggest that Cerebrolysin may offer neuroprotective benefits to mitigate cognitive deficits associated with chemotherapy. pubmed.ncbi.nlm.nih.gov

Considerations:

While these preliminary findings are promising, it’s important to note that the current body of research is limited, primarily involving animal models. Further studies, including clinical trials with human participants, are necessary to comprehensively understand Cerebrolysin’s efficacy and safety profile in cancer-related applications. Patients should consult with their healthcare providers before considering Cerebrolysin as part of their treatment regimen.

Does the RealWorld Feedback live up to the “hype” – claimed benefits?

Updated 1-2-25 

  • Yes Cerebrolysin in my experience and feedback has life changing potential which puts it into a truly unique class of “tools”
  • For neuroinflammation, ADD/ADHD/ASD, TBI, Cogntive Performance, Sport Performance, Anxiety – Stress, Alzheimers – Dementia it is absolutely worth researching!
  • Cerebrolysin without a doubt gets Project Biohacked stamp of approval
  • Cerebrolysin is in Top 3 categories for Neuroinflammation, ADD/ADHD, Stress – Anxiety and a handful of other target goals – conditions. 🏆
  • Another Low RISK, Potentially High Reward tool well worth researching.
  • But like ALWAYS do your own independent research this is a BIOLOGIC compound in that it is animal derived.
  • There is absolutely a SIDE EFFECTs profile.
  • It is NOT 100% success rate as far as noticed benefits within my community, it is generally very positive feedback but not everyone notices benefits.

Mechanism of Action: How Does Cerebrolysin Work?

Neurotrophic Activity – Mimicking Growth Factors

Cerebrolysin acts similarly to endogenous neurotrophic factors, which are essential for neuron survival, differentiation, and repair. It enhances:

✅ Brain-Derived Neurotrophic Factor (BDNF):

  • Promotes synaptic plasticity (crucial for learning and memory).
  • Increases long-term potentiation (LTP), the mechanism behind memory formation.

✅ Nerve Growth Factor (NGF):

  • Supports survival and function of cholinergic neurons (critical for memory, impaired in Alzheimer’s).
  • Promotes axon regeneration and dendritic branching.

✅ Glial Cell Line-Derived Neurotrophic Factor (GDNF):

  • Protects dopaminergic neurons (important in Parkinson’s disease).
  • Aids motor recovery after stroke or injury.

✅ Ciliary Neurotrophic Factor (CNTF):

  • Supports neurogenesis and oligodendrocyte survival (important for myelin repair).

✅ Insulin-Like Growth Factor-1 (IGF-1) Fragments:

  • Stimulates neuronal regeneration and repair post-injury.
  • Enhances brain metabolism and energy production.

🚀 Impact:

Cerebrolysin replicates the effects of multiple neurotrophic factors simultaneously, promoting brain repair, synaptic connectivity, and neuroplasticity.

Neuroprotection – Shielding the Brain from Damage

Cerebrolysin provides strong neuroprotective effects, helping neurons survive against:

✅ Excitotoxicity (Glutamate Toxicity):

  • Inhibits excessive NMDA receptor activation, preventing neuronal damage.

✅ Oxidative Stress:

  • Reduces free radical damage by enhancing endogenous antioxidant defenses.
  • Preserves mitochondrial function, preventing energy deficits.

✅ Apoptosis (Programmed Cell Death):

  • Inhibits caspase activation, preventing neurodegeneration.
  • Promotes anti-apoptotic proteins like Bcl-2, keeping neurons alive.

✅ Neuroinflammation Modulation:

  • Reduces overactivation of microglia, preventing chronic inflammation.
  • Decreases pro-inflammatory cytokines (IL-1β, TNF-α), protecting neurons.

🚀 Impact:

Cerebrolysin protects neurons from inflammation, oxidative stress, and apoptosis, making it beneficial for stroke, Alzheimer’s, traumatic brain injury, and neurodegeneration.

Enhancing Synaptic Plasticity & Cognitive Function

Cerebrolysin enhances synaptic plasticity, which is crucial for learning, memory, and cognitive flexibility. It does this by:

✅ Increasing Dendritic Spine Density:

  • Strengthens synaptic connections, improving memory formation.

✅ Enhancing Long-Term Potentiation (LTP):

  • Boosts synaptic strength, critical for learning and memory storage.

✅ Modulating Key Neurotransmitters:

  • Dopamine → Enhances motivation, focus, and mood (useful for ADHD & depression).
  • Acetylcholine → Improves memory and attention (critical in Alzheimer’s).
  • Glutamate/GABA balance → Regulates excitatory/inhibitory balance for mental clarity.

🚀 Impact:

Cerebrolysin enhances cognitive performance, memory consolidation, and mental clarity, making it effective for ADHD, brain fog, and cognitive decline.

Neurogenesis – Stimulating Brain Repair & Growth

Cerebrolysin promotes neurogenesis (growth of new neurons), particularly in the hippocampus, the brain’s memory center.

✅ Increases Neural Stem Cell Differentiation:

  • Encourages new neurons to develop, aiding brain repair after injury.

✅ Boosts Myelination & Axonal Growth:

  • Helps restore white matter integrity, critical for processing speed.

🚀 Impact:

Cerebrolysin supports brain recovery after stroke, traumatic brain injury, and neurodegeneration.

Enhancing Brain Metabolism & Energy Production

Cerebrolysin improves mitochondrial function and ATP production, reducing mental fatigue and supporting cognitive endurance.

✅ Increases Glucose & Oxygen Utilization in the Brain:

  • Helps neurons function efficiently, even in low-oxygen states (e.g., stroke recovery).

✅ Supports Mitochondrial Health:

  • Reduces oxidative damage to mitochondria, preventing energy deficits.

🚀 Impact:

Cerebrolysin combats brain fog, fatigue, and metabolic dysfunction in conditions like chronic fatigue syndrome and post-COVID brain fog.

Review of Literature: Studies on Cerebrolysin: 

Clinical Trial Registries:

  • EU Clinical Trials Register: A search for “Cerebrolysin” yields 7,345 clinical trials involving human subjects.
    clinicaltrialsregister.eu
  • PubMed Database: A search for “Cerebrolysin” in clinical trials results in 1,773 studies.
    cochrane.org

Notable Studies:

  • Stroke Recovery: A prospective, randomized, double-blinded, placebo-controlled, multicenter study enrolled 100 patients within 18 hours after the onset of stroke to evaluate the safety and efficacy of Cerebrolysin in early recovery.
    pmc.ncbi.nlm.nih.gov
  • Vascular Dementia: A systematic review and meta-analysis assessed the effects of Cerebrolysin on functional outcomes in patients with traumatic brain injury, indicating potential benefits.

Stroke Recovery

  • Cerebrolysin and Recovery After Stroke (CARS) Study (2015):
    • Objective: Evaluate the efficacy of Cerebrolysin in early rehabilitation post-stroke.
    • Findings: Patients receiving Cerebrolysin showed significant improvements in functional outcomes and global recovery compared to placebo. The safety profile was comparable between both groups. ahajournals.org
  • Cerebrolysin in Acute Ischemic Stroke in Asia (CASTA) Trial (2012):
    • Objective: Assess the efficacy of Cerebrolysin in acute ischemic stroke patients.
    • Findings: No significant difference in primary outcomes between Cerebrolysin and placebo groups. However, a subgroup analysis indicated potential benefits in patients with more severe strokes (NIHSS >12). ahajournals.org
  • Cochrane Review on Cerebrolysin for Acute Ischemic Stroke (2023):
    • Objective: Systematically review randomized controlled trials on Cerebrolysin’s efficacy and safety in acute ischemic stroke.
    • Findings: Adding Cerebrolysin to standard therapy probably offers no benefit in reducing mortality risk post-stroke. Some studies reported a higher rate of adverse events requiring hospitalization. cochrane.org

Traumatic Brain Injury (TBI)

  • Efficacy and Safety of Cerebrolysin in Neurorecovery After Moderate to Severe TBI (2019):
    • Objective: Investigate Cerebrolysin’s effects on recovery following moderate to severe TBI.
    • Findings: Cerebrolysin administration led to improved overall outcomes, as measured by a multidimensional approach, supporting its potential as a beneficial treatment in TBI recovery. pubmed.ncbi.nlm.nih.gov

Neuroprotection and Neuroplasticity

  • Randomized, Placebo-Controlled, Double-Blind Pilot Trial (2020):
    • Objective: Assess Cerebrolysin’s safety and efficacy in patients with aneurysmal subarachnoid hemorrhage.
    • Findings: Cerebrolysin enhanced neuroplasticity by promoting synaptic remodeling and neurogenesis in the peri-infarct zone, suggesting potential benefits in brain repair mechanisms. bmcneurol.biomedcentral.com

Safety Profile

  • Safety of Cerebrolysin for Neurorecovery After Acute Ischemic Stroke (2021):
    • Objective: Evaluate the safety of Cerebrolysin in acute ischemic stroke patients.
    • Findings: Cerebrolysin successfully crosses the blood–brain barrier and was generally well-tolerated, with a safety profile comparable to placebo.

Does Cerebrolysin have FDA Approval:

Cerebrolysin is approved for medical use in over 50 countries, primarily across Europe and Asia. Its approved therapeutic indications include:

  • Dementia: Both Alzheimer’s disease and vascular dementia.
  • Stroke: Assisting in recovery post-stroke.
  • Traumatic Brain Injury: Supporting rehabilitation following brain injuries.

However, Cerebrolysin has not received approval in certain countries, including the United States and Australia.

Vetted Suppliers for Cerebrolysin:  (For RESEARCH PURPOSES ONLY)

Important Reminder: Peptides purchased direct online do not come with instructions, they come in lyophilized powder form and need to be reconstituted at the proper ratio. To research peptides purchased direct SELF EDUCATION is a MUST.

I have peptide education resources listed below that cover calculating dosages, supplies needed and reconstituting.

Cosmic Nootropics: 🇺🇸

Favorite supplier for Cerebrolysin, Cortexin and some other unique compounds 🙂

Group Discount Code: projectbiohacked10 (10% off orders) – https://cosmicnootropic.com/products/cerebrolysin/

  • For those completely NEW to Cerebrolysin I would opt for 2ml ampules or 5ml at most to gauge tolerance.
  • Make sure to select shipping from their US warehouse. You can definitely save some money opting for delivery from their international warehouse but it’s 20-30 day shipping and on rare occasion someone reports package getting stopped by customs. I would personally just go with US Warehouse.

Limitless Life Nootropics🇺🇸

  • Limitless offers single ampules but currently isnt allowing discount code. But I spoke with them today and I believe they will be allowing the code! Soon as I get those details I will update guide 🙂

OTHER Supplies needed:

Important Reminder: Peptides purchased online are sold FOR RESEARCH PURPOSES ONLY. This means:

  • Purchasing direct online for research means you take 100% responsibility for knowing how to SAFELY research.
  • Vendors will NOT advise you on how to research these compounds. They are sold for research purposes and it is a huge liability and legal risk for vendors to advise on usage. Certain vendors will blacklist those who email asking about human usage.
  • Be Prepared: If you are unfamiliar with how to research peptides safely, I highly recommend enrolling in a peptide education course or working with a qualified coach or practitioner.
  • Peptide Education course offer & other resources below if interested!

DOSING:

(Educational Purpose ONLY – Project Biohacked LLC – Always consult your physician before making any changes to your medical treatment plan)

Subcutaneous (SC) Administration (Lower Doses, More Frequent Use)

SC administration is an emerging approach for self-administration and long-term use at lower doses.

Standard SC Dosing Guidelines
  • Microdosing protocol: 1–2 mL per injection, daily or every other day, for 4–6 weeks
  • Moderate protocol: 2–5 mL per injection, 5 days per week, for 4–8 weeks
  • Intensive protocol (TBI, Stroke Recovery): 5–10 mL per injection, daily for 10–20 days, then taper

SC injections are best administered in the abdomen, thighs, or upper arms, rotating sites to avoid irritation.

Intramuscular (IM) Administration (Alternative to IV)

IM administration is widely used in outpatient settings and self-administration protocols.

Standard IM Dosing Guidelines
  • Mild cognitive enhancement: 1–5 mL per day for 10–30 days
  • Neurodegenerative conditions (Alzheimer’s, Parkinson’s): 5–10 mL daily for 20–30 days
  • TBI / stroke recovery: 10–20 mL daily for 10–30 days

Best practice: IM injections should be rotated between different muscle groups (glutes, deltoid, or thigh) to prevent irritation.

Cyclic Protocol for Long-Term Use

For chronic neurodegenerative diseases, cognitive enhancement, or stroke recovery, a cyclic approach is often used:

  • Cycle length: 4–6 weeks of daily or alternate-day dosing
  • Break period: 4–8 weeks off before restarting
  • Number of cycles per year: 2–3 cycles annually for long-term benefits

This allows the body to maintain neuroplasticity benefits while avoiding desensitization to the treatment.

Full Dosage Range for Cerebrolysin:
  • “Microdose” – Test Dose (.25ml – .5ml): good test dose for those who are highly “chemical sensitive”, Mold – CIRs, Lyme
  • Low – Moderate Dose(1ml): good test dose for those who prefer to start low to gauge tolerance
  • Moderate Dose (2ml): good dose for healthy individuals who rarely have any sensitivities – reactions
  • Moderate High(5ml): healthy subjects w/ no sensitivities or slowly TITRATED UP TO
  • High (10ml+): you are bulletproof, rarely ever react to anything or slowly TITRATED UP TO
Notes on my personal usage – Approach:

The following is for INFORMATIONAL Purposes only, this is NOT MEDICAL advice, I AM NOT a medical professional, please consult with your physician before making any changes to your medical treatment plan. 

  • Being someone who is EXTREMELY sensitive to exogenous compounds I had to go with a very conservative approach.
  • This is also the approach I typically recommend to clients – community
  • Start LOW Start Slow
  • Using the above Dosage range LOW for myself was just .5ml was PLENTY
  • Even at just .5ml I had day of brain fog – mild head pressure thats COMMON with neurogenic compounds like Cerebrolysin. People have also reported feeling fatigued and even irritable.
  • Which YES those side effects do not sound appealing but I also noticed when the side effects went away I felt better overall. I noticed this rather quickly and this is what MAY happen for some who responds extremely well like myself.
  • Those side effects for myself only occurred during first couple dosages and or when I dosed to HIGH and or to frequently.
  • So I DID NOT stick to a traditional dosing approach like laid out by the manufacturer EVERPHARMA. If I did a traditional protocol of 2-5ml for 30 days the brain fog would have been significant along with myriad of other side effects.
MY PERSONAL Approach:
  • .5ml first test dose
  • I had brain fog, some fatigue and irritability that day which happens to some but NOT EVERYONE
  • I essentially would wait until I felt back at baseline before dosing again.
  • Which means I typically would only dose 3-4x per week or even less.
  • I did this for longer cycles because the benefits were so great honestly I just didn’t want to stop and felt I was much lower on the dosage. I am NOT saying I advise this its just what I did.
  • I slowly over the first year titrated to doses as high as 10ml. But my “sweet spot” was typically 2ml-5ml couple times per week and I was able to maintain very high mental performance. I also felt lasting benefits from the cycles. But I am ADD/ADHD, have history of TBI and issues with anxiety. So this tool just happened to be a perfect fit and likely was healing some damage and imbalances. However I have heard from other high performers that they also felt fantastic benefits. So it can be for those simply looking to achieve their peak potential performance wise.
  • My cycles went much longer but it’s not something I recommend unless you have carefully weighed the pros and potential cons. I have never experienced negatives but there is a side effect profile that should be fully evaluated.

Quick Summary:

  • Start Low and Slow
  • Test Dose – Gauge tolerance and response
  • Titrate dose and frequency until you reach max benefits with minimal side effects
  • What that may look like per person will vary greatly and is highly dependent on primary goals and or condition looking to treat!
  • Ive now cycled Cerebrolysin for 4+ years and it’s one of my all time favorite tools. I have countless reports now that it’s equally life changing for others.
  • Again NOT for everyone has this experience but when theres a low risk potentially high reward tool that could change somones life then I like to talk about it!! 🙂

Clinical studies investigating Cerebrolysin have typically administered the treatment for durations ranging from 4 to 21 days. For instance, a double-blind, placebo-controlled, multicenter study assessed the efficacy and safety of Cerebrolysin over a 4-week (28-day) period in patients with probable Alzheimer’s disease.

pubmed.ncbi.nlm.nih.gov

Similarly, in the Cerebrolysin and Recovery After Stroke (CARS) trial, the treatment period extended up to 21 days.

ahajournals.org

These durations are among the longest reported in clinical trials evaluating Cerebrolysin’s efficacy and safety.

OTHER Cerebrolysin Resources:

UNLISTED Youtube Video Tutorial I did on Cerebrolysin:

https://youtu.be/Iuf-SfawFaw?si=X5ZCm0xdczuGCvo5

Video Review I did 2 years ago talking about my Cerebrolysin experience:

https://youtu.be/3tc22MDVsy8?si=IKX8gP_sCHrjUW7m

SAMPLE Protocols Based on Goals: 

Cognitive Enhancement, ADHD, Brain Fog

Goal: Improve focus, memory, executive function, and mental clarity.

  • Dose: 1–5 mL (IM or SC), once daily or every other day
  • Duration: 10–30 days per cycle
  • Break: 4–6 weeks before repeating
  • Repetition: As needed for sustained cognitive benefits
  • Optional: Combine with Citicoline (500 mg/day) or Noopept (10–30 mg/day) for added cognitive benefits.

Mild Cognitive Impairment (MCI) & Age-Related Decline

Goal: Slow cognitive decline, support neuroprotection, and enhance brain plasticity.

  • Dose: 5 mL (IM or SC) daily
  • Duration: 20–30 days per cycle
  • Break: 6–8 weeks before restarting
  • Repetition: 2–3 cycles per year for long-term benefits.

Stroke Recovery & Traumatic Brain Injury (TBI)

Goal: Enhance neuroregeneration, improve motor and cognitive recovery.

  • Dose: 10–20 mL (IM – IV), once daily
  • Duration: 20–30 days per cycle
  • Break: 6–8 weeks before next cycle
  • Repetition: 2–3 cycles per year, depending on severity of injury.
  • Optional: Stack with Citicoline (1,000 mg/day) and Omega-3 (2 g/day) for additional neuroregeneration.

Alzheimer’s Disease & Parkinson’s Disease

Goal: Slow neurodegeneration, support synaptic plasticity, and enhance cognition.

  • Dose: 10–30 mL (IM – IV), once daily
  • Duration: 20–30 days per cycle
  • Break: 6–8 weeks before repeating
  • Repetition: 2–3 cycles per year
  • Optional: Combine with Memantine (5–20 mg/day) or Selegiline (5 mg/day) for Parkinson’s.

Anxiety, Depression, and Mood Regulation

Goal: Modulate neuroplasticity and neurotransmitter balance for improved mood and resilience.

  • Dose: 1–5 mL (SC or IM), daily or every other day
  • Duration: 10–30 days per cycle
  • Break: 4–6 weeks before repeating
  • Optional: Stack with L-Theanine (200 mg/day) or Ashwagandha (500 mg/day) for enhanced mood support.

Long-Term Neuroprotection & Anti-Aging

Goal: Maintain cognitive function, prevent age-related neurodegeneration, and support brain health.

  • Dose: 1–5 mL (SC), 3–5 times per week
  • Duration: 4–6 weeks per cycle
  • Break: 6–8 weeks before repeating
  • Repetition: 2–3 cycles per year for ongoing neuroprotection.

Post-COVID or Post-Viral Brain Fog & Fatigue

Goal: Improve cognitive function, reduce neuroinflammation, and restore mental clarity.

  • Dose: 1- 5 mL (IM or SC), once daily
  • Duration: 10–30 days per cycle
  • Break: 4–6 weeks before repeating
  • Optional: Combine with NAC (600–1,200 mg/day) and Alpha-GPC (300 mg/day) to aid in recovery.

Side Effects and Contraindications of Cerebrolysin:

Cerebrolysin is generally well-tolerated, but like all medications, it can cause side effects and has specific contraindications.

Common Side Effects:

  • Injection Site Reactions: Pain or redness at the injection site.

Commonly Reported Side Effects:

Less Common but Notable Side Effects:

  • Elevated Blood Pressure: Some users have experienced an increase in blood pressure, necessitating regular monitoring, especially in those with pre-existing hypertension.
    synapse.patsnap.com
  • Palpitations: Reports of irregular heartbeats or palpitations have been noted.
    synapse.patsnap.com
  • Severe Allergic Reactions: Although rare, there have been documented cases of severe anaphylactic reactions following intravenous administration of Cerebrolysin. onlinelibrary.wiley.com

Administration-Related Observations:

Rapid injection of Cerebrolysin may lead to sensations of warmth, increased sweating, dizziness, heart palpitations, or irregular heartbeats. To minimize these effects, it is recommended to administer the injection slowly. cosmicnootropic.com

What about PRIONS risk? 

Regarding Cerebrolysin, there is no scientific evidence to suggest that it contains prions or could lead to prion-related diseases. Cerebrolysin is a mixture of peptides and amino acids derived from porcine brain tissue, and while it is a biologically active substance, it does not appear to possess the properties that could cause prion diseases.

Key points to consider:

  1. Manufacturing Process: Cerebrolysin undergoes a rigorous manufacturing process designed to ensure safety, including filtration and purification steps. The risk of prion contamination is extremely low due to these controls.
  2. Regulatory Approval: Cerebrolysin has been approved in multiple countries for the treatment of neurodegenerative diseases, and there have been no reports of prion-related side effects associated with its use.
  3. Scientific Literature: There is no evidence in the scientific literature indicating that Cerebrolysin could cause prion diseases. The potential risks of prions are more associated with diseases like CJD or other transmissible spongiform encephalopathies (TSEs), which are distinct from the known effects of Cerebrolysin.

Therefore, while the theoretical risk of prion formation exists with any substance derived from animal tissues, it is considered highly unlikely with Cerebrolysin due to the lack of evidence and the extensive processing involved in its production. Nonetheless, as with any medical treatment, it is important to use Cerebrolysin under the guidance of a healthcare professional.

Conclusion:

While Cerebrolysin is generally considered safe and well-tolerated, individuals may experience a range of side effects, from mild to severe. It is crucial to consult with a healthcare provider before starting treatment to ensure proper monitoring and management of any adverse reactions.

Medical Disclaimer:

The information provided about peptides is for educational purposes only and should not be considered medical advice. Peptide therapy is not approved by all regulatory agencies and may be considered experimental in some regions. Always consult a licensed healthcare professional before starting any peptide treatment to determine its safety, efficacy, and appropriateness for your specific health condition. Use of peptides should be supervised by qualified medical personnel, and individuals should be aware of potential risks, side effects, and contraindications. This content does not replace professional medical consultation or diagnosis.

Full List of Suppliers I personally VET: 

I know the owners, I know their customer service teams and I WILL STEP in to help with ANY issues with your orders!!

If you love the content and want to support using my affiliate links it’s greatly appreciated and helps me afford the time to make high quality FREE content for the community which I love doing 🙂

But no pressure!! Even if you just support by just giving quality feedback in the group and good vibes thats appreciated to!! 🙂

**ATOMIK Peptides 🇺🇸

  • Tirz Research – 3rd Party Batch Tested
  • Get 15% off with discount code: Biohacked15

Solution Peptides 🇺🇸

  • 2024 1st Place in Voting for Favorite Peptide Supplier!!
  • Reta, Sema, NAD+, Peptides, Vitamins
  • Full 3rd party testing reports and great feedback from community on this supplier.** **
  • Get 15% with Group Discount Code: Biohacked15 

Limitless Life Nootropics 🇺🇸

  • 2024 2nd Place in Voting for Favorite Peptide Supplier!!
  • Get 20% off with Group Discount Code: Biohacked20

BioSynergen Peptides: 🇨🇦

  • Tirz Research Stocked
  • Get 10% off with Group Discount code: Biohacked10

CosmicNootropic.com

  • Cerebrolysin, Cortexin, Peptide Bioregulators
  • Get 10% off with Group Discount Code: projectbiohacked10

LVLUPhealth.com

  • For the BEST Oral Peptide Formulations – GI Healing – BPC157
  • Get 10% off with Group Discount Code: Biohacked10

DN Lab Research

  • Fully operational for our **UK/EU and UAE Members!! **
  • Discount Code: Biohacked15

Promethean Bioregulators

  • US Based Peptide Bioregulator supplier – They STOCK and SHIP from the US!! AKA Fast Shipping
  • They have FULL line of CYTOMAX Bioregulators. These are the full strength natural bioregulators that you see being sold at Cosmic, Qi, Profound Health ETC. They are batch tested for purity and have all the quality reports for each product.
  • Boxes each contain 20 caps which covers a STANDARD protocol of 2 caps per day for 10 days. Approaches vary depending on individuals health goal/situation/severity.
  • Get 10% off with Group Discount Code: Biohacked10

About the Author 

Jeff 2000x2000

Jeff Robinson B.S. Exercise Physiology
Human Performance – Project Biohacked LLC

I graduated from Southern CT University in 2011 with a Bachelors Degree in Exercise Physiology Human Performance.

I’ve been health coaching/consulting privately now for 15+ years and have worked with individuals of all ages and health concerns/goals.

Professional Work Experience:

  • Griffen Hospital Cardiac Rehab
  • Yale Strength and Conditioning
  • IAP Sports Training
  • Revelry Wellness HRT Telehealth Clinic (Now Transcend Wellness)
  • My Summit Health Telehealth Clinic (HRT/TRT, Peptides)

One of my favorite tools to educate clients on is of course PEPTIDE Therapy!!

Peptide therapy truly was that one tool that FINALLY took me from chronic health struggles to seeing FULL remission of some of those issues.

It’s a tool I’ve seen aid chronic and or acute health struggles when EVERYTHING ELSE had failed.

Peptides really restored my faith in modern medicine, introduced me to the amazing world of regenerative – cellular medicine that is at the cutting edge of health optimization and chronic degenerative conditions. And these tools have been used for DECADES!!

There are currently over 100 peptide drugs with FDA approval.

They are just rarely discussed and I’m trying to change that!! :))

I created the health brand Project Biohacked 5 years ago specifically to share about peptide therapy and **How it was life changing for my own health struggles.**
**(ADD/ADHD, TBI, PTSD, Anxiety, Depression, Addiction, GI Inflammation)**

My “brand” Project Biohacked mission is ALL ABOUT finding the best tools and health/wellness.

The stuff that’s buried far away from mainstream medicine, the stuff that’s proven safe and effective yet is never used by those in the Allopathic Medical system!!

 

Project Biohacked Mission Statement:

It is important to me that people understand my WHY. I want people to fully understand what I am trying to do with the Project Biohacked brand.

This is relevant to peptides since they are one of the tools that forever changed my life for the better and restored my hope I could fully recover my health!

My reason WHY has everything to do with my own at times extremely difficult health journey.

This life has not always been an easy ride for myself, I have experienced levels of suffering with my own health physically and mentally that I wouldn’t wish upon my worst enemy.

I have been left broken and feeling hopeless from those struggles at the worst points in my life. I have been told by the conventional medical system there’s nothing I can do. That pharmaceutical drugs to suppress symptoms are the only way to manage my struggles.

I have hit that wall in my health over and over again where I felt like I was out of options and destined to suffer through this life.

I also know I am not the only one who has gone through and or still has these chronic struggles. I know countless others suffer in silence, bearing a burden that no one even knows about. Too many suffer in silence especially with mental health and or addiction struggles. This includes myself.

I have lost loved ones to physical illness and mental health struggles. I think we all know someone who didn’t make it past their physical/mental health struggle. We all have lost people we love. I have seen far too many suffer horribly from these chronic health struggles when the tools to help are available and accessible NOW.

I have been to the bottom with my health….. but I have also been to the top!

I have experienced the joy of not just recovering physical and mental health but getting to experience all new highs with both. Having the luxury to shift my focus from chronic health to anti aging and chasing peak physical/mental performance!!

I have been able to recover and go on to experience days, months and years feeling good again. Days where I have felt happy, at peace and content with life. Days I have been able to be fully present with loved ones and just enjoy the simple things in life.

This is something I wish everyone would get to experience as much as possible in their lives.

I am lucky to have fully recovered from the worst of my health struggles, I am lucky to still be here today, to see my kids grow and be there for my family.

Far too many lose that battle because they lose HOPE. They lose hope because they feel like theres nothing that can help. They believe theres no end to their suffering.

Thankfully I learned this is not TRUE!! There are amazing tools that can get not just RELIEF but actual healing! Far too many of these amazing tools people simply do not know exist!

Luckily I found some of these amazing tools that kept that hope alive.

Somehow I found a way to survive my health crisis and I made the decision then that I would leave no stone left unturned in this life to not just recover my health but to find the tools to ensure I NEVER experienced that level of suffering again.

I committed myself to try to LEARN EVERYTHING in regard’s to healing the mind, body and spirit. I would study every facet of medicine, I would try everything that I could afford and access.

My promise to myself was if I somehow did recover my health I would reach back to try and help others.

I would share my story, I would share what helped me and I would make it my mission to try and help others struggling. I would leave a roadmap for those suffering. A roadmap and guide that could possibly help restore hope of better days.

I decided to try and create the resource that I wish existed when my health fell apart.

A resource that could quickly get someone to the tools that can make all the difference in their health struggles and goals. A resource that helped restore HOPE that just maybe better days were still possible.

A resource that shares the tools buried far beyond the conventional medical and health system. The “tools” that can change lives but many don’t know even exist.

It took me over 15 years of relentless research trial and error to find all of the tools to aid in my recovery.

Few have that kind of time, resources and energy to take on.

My goal is to help accelerate that process for people. Get people pointed to the life changing tools much earlier in their journey. Hopefully prevent some from experiencing the horrible lows I did in my own health.

At the end of my days I hope to have created a massive DIY health resource that can change lives for the better.

Help people get to experience their true potential, become the best versions of themselves. Help pass along tools that can aid people and the people they love/care about most.

The mission that will never end is to hunt down and share all the best tools in health and wellness. To refine and update these resources every year as better tools and understanding emerges for all ranges of chronic health struggles/recovery.

The focus will go beyond just chronic health struggles, it will deep dive into physical performance and mental performance. Anti aging and the best sustainable practices to feel our best for the longest period of time possible in this life.

What I LOVE is bringing light to not just the best tools but the best practitioners, the best coaches and clinics. The people who understand how to pull all the best tools together to change lives for the better. Bring together and share what I learn from the best minds in health and wellness.

The goal is to create a massive network that can continue to pass these tools to others long after I’m gone.

That is my mission, that is the reason I do what I do 🙂

I love networking with other health professionals, coaches and biohackers so feel free to reach out if interested in doing a podcast or partnering on a project 🙂

Jeff Robinson
Project Biohacked LLC